scholarly journals CD8+ T cell apoptosis induced by Escherichia coli heat-labile enterotoxin B subunit occurs via a novel pathway involving NF-κB-dependent caspase activation

2002 ◽  
Vol 32 (6) ◽  
pp. 1737 ◽  
Author(s):  
Robert J. Salmond ◽  
Richard S. Pitman ◽  
Eijiro Jimi ◽  
Marco Soriani ◽  
Timothy R. Hirst ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
T Cell ◽  
Cell Apoptosis ◽  
Cd8 T Cell ◽  
Caspase Activation ◽  
T Cell Apoptosis ◽  
B Subunit ◽  
Heat Labile ◽  
Enterotoxin B

Tissue culture and expression of Escherichia coli heat-labile enterotoxin B subunit in transgenic Peperomia pellucida

2010 ◽  
Vol 72 (1) ◽  
pp. 82-86 ◽  
Author(s):  
Nguyen Hoang Loc ◽  
Nguyen Hoang Bach ◽  
Tae-Geum Kim ◽  
Moon-Sik Yang
Keyword(s):  
Escherichia Coli ◽  
Tissue Culture ◽  
B Subunit ◽  
Heat Labile ◽  
Enterotoxin B

scholarly journals Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis

2019 ◽  
Vol 144 (9) ◽  
pp. 2290-2302 ◽  
Author(s):  
Lenneke A.M. Cornelissen ◽  
Athanasios Blanas ◽  
Joost C. van der Horst ◽  
Laura Kruijssen ◽  
Anouk Zaal ◽  
...  
Keyword(s):  
Sialic Acid ◽  
T Cell ◽  
Tumor Growth ◽  
Cell Apoptosis ◽  
Acid Metabolism ◽  
Cd8 T Cell ◽  
T Cell Apoptosis

scholarly journals Escherichia coli Heat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin

2001 ◽  
Vol 69 (5) ◽  
pp. 3476-3482 ◽  
Author(s):  
Douglas G. Millar ◽  
Timothy R. Hirst ◽  
Denis P. Snider
Keyword(s):  
Escherichia Coli ◽  
Cholera Toxin ◽  
Lymphocyte Proliferation ◽  
Vaccine Adjuvants ◽  
B Subunit ◽  
Heat Labile ◽  
Antibody Titers ◽  
Enterotoxin B ◽  
Draining Lymph Nodes ◽  
Stimulation Of

ABSTRACT Although cholera toxin (Ctx) and Escherichia coliheat-labile enterotoxin (Etx) are known to be potent mucosal adjuvants, it remains controversial whether the adjuvanticity of the holotoxins extends to their nontoxic, receptor-binding B subunits. Here, we have systematically evaluated the comparative adjuvant properties of highly purified recombinant EtxB and CtxB. EtxB was found to be a more potent adjuvant than CtxB, stimulating responses to hen egg lysozyme when the two were coadministered to mice intranasally, as assessed by enhanced serum and secretory antibody titers as well as by stimulation of lymphocyte proliferation in spleen and draining lymph nodes. These results indicate that, although structurally very similar, EtxB and CtxB have strikingly different immunostimulatory properties and should not be considered equivalent as prospective vaccine adjuvants.

Mass production of somatic embryos expressing Escherichia coli heat-labile enterotoxin B subunit in Siberian ginseng

2006 ◽  
Vol 121 (2) ◽  
pp. 124-133 ◽  
Author(s):  
Tae-Jin Kang ◽  
Won-Seok Lee ◽  
Eun-Gyung Choi ◽  
Jae-Whune Kim ◽  
Bang-Geul Kim ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Mass Production ◽  
Somatic Embryos ◽  
B Subunit ◽  
Siberian Ginseng ◽  
Heat Labile ◽  
Enterotoxin B

scholarly journals Association of CD8 T cell apoptosis and EGFR mutation in non‐small lung cancer patients

2020 ◽  
Vol 11 (8) ◽  
pp. 2130-2136
Author(s):  
Chao Zhao ◽  
Chunxia Su ◽  
Xuefei Li ◽  
Caicun Zhou
Keyword(s):  
Lung Cancer ◽  
T Cell ◽  
Cancer Patients ◽  
Cell Apoptosis ◽  
Egfr Mutation ◽  
Cd8 T Cell ◽  
Lung Cancer Patients ◽  
T Cell Apoptosis
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